Abstract Background Intravascular fasciitis (IVF) is a rare benign condition characterised by reactive myofibroblastic proliferation arising from the superficial or deep fascia and involving arteries and/or veins.It is a distinct variant of the Brush more common condition of nodular fasciitis, which possesses similar clinical and histological features to IVF, but lacks vascular invasion.A thorough review of the literature revealed 26 reported cases of IVF.Case presentation We report a case of IVF in a 16-week pregnant lady affecting the hypothenar eminence of the hand associated with Vase Bongs the ulnar artery.Conclusion The characteristic involvement of muscular arteries and veins by reactive myofibroblastic proliferation in IVF suggests a malignant component and often leads to an inappropriate diagnosis for this benign condition.
We propose that hormone-related changes associated with pregnancy may play an important role in the aetiopathogenesis of this myofibroblastic lesion.